#4D6D88_Small Cover_March-April 2024 DRA Journal

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CBD Potential Alternative for Dental Pain Management

USA: A recent study published in the Journal of Dental Research has revealed the potential of CBD (cannabidiol) as a safe and effective alternative to opioids for acute dental pain, marking a significant advancement in pain management and opioid alternative research. Conducted by scientists from Rutgers University and the University of Texas, the study points to a promising new direction in addressing the opioid epidemic through cannabis-based solutions.

Study Methodology and Findings

“In this study, adults with moderate to severe dental pain were administered Epidiolex, an FDA-approved CBD medication, to evaluate its effectiveness in pain management compared to a placebo,” stated the research findings. 

Read: Cannabidiol Shows Promise as Non-Opioid Analgesic in Dental Pain Management

“The findings indicated that participants treated with CBD experienced a notable decrease in pain levels. Moreover, those who received a higher dosage of CBD reported a faster onset of pain relief.” These results underscore CBD’s potential as a viable alternative to opioid medications for acute dental pain treatment.


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The study’s encouraging results highlighted CBD’s comparable efficacy to traditional analgesics used in dental emergencies. “Not only did CBD treatment alleviate pain, but it also improved bite force among subjects, essential for dental health and overall quality of life,” the study noted. 

However, researchers noted some side effects associated with CBD use, such as sedation, diarrhea, and abdominal pain, emphasizing the need for further research to solidify CBD’s safety profile in pain management.

Read: New Evidence-Based Guideline for Managing Acute Dental Pain Issued

Insights from Industry Experts

Dr. Chanda Macias, CEO of National Holistic Healthcare and a prominent figure in the cannabis industry, has previously acknowledged the efficacy of CBD for pain relief and inflammation in oral care diseases. 

“Like all medications, finding the ideal one for each patient and their symptoms involves an element of trial and error,” Dr. Macias highlighted. “Some conditions, for example, have been shown to be responsive to higher amounts of CBD and less THC, so that’s where formulations matter.” Dr. Macias emphasized the importance of individualized treatment plans and optimal delivery methods based on patient conditions.

Implications for Pain Management Practices

“As the cannabis industry evolves, the study represents a critical step forward in integrating CBD into mainstream medical practices for pain management,” stated the researchers. “With anticipated FDA approval for Epidiolex or similar CBD solutions in dental pain management, patients may soon have access to more effective and safer alternatives to opioids for treating acute toothache and potentially other pain conditions.” 

With the potential for CBD to revolutionize dental pain management, further research and regulatory approvals are essential to ensure its widespread adoption and safe use in clinical settings. The findings of this study offer promising prospects for addressing dental pain while mitigating the risks associated with opioid use.

Read: NSAIDs and Acetaminophen Recommended as First-Line Dental Pain Relief

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