Cov kws tshawb nrhiav Uncover Synergistic Treatment For Dental Caries Prevention

TEB CHAWS USA: Kev tshawb nrhiav kev ua tiav coj los ntawm Hyun (Michel) Koo ntawm University of Pennsylvania Lub Tsev Kawm Ntawv Kho Hniav Tshuaj thiab David Cormode ntawm Penn's Perelman Tsev Kawm Ntawv Tshuaj qhia txog kev cog lus muaj txiaj ntsig hauv kev tiv thaiv kab mob. 

Lawv cov kev tshawb fawb, luam tawm hauv Nature Communications, nthuav tawm qhov ua tau zoo ntawm kev sib txuas ntawm ferumoxytol (Fer) thiab stannous fluoride (SnF2).

Holistic Approach to Caries Prevention

Koo hais txog, "Peb cov kev kho mob ua ke tsis yog tsuas yog ua kom muaj txiaj ntsig zoo ntawm txhua tus neeg sawv cev tab sis ua li ntawd nrog cov tshuaj qis dua, qhia txog qhov muaj peev xwm hloov pauv txoj kev tiv thaiv kab mob caries hauv cov neeg muaj kev pheej hmoo siab." Txoj hauv kev tshiab no hais txog cov kev txwv ntawm kev kho ib txwm siv los ntawm kev tsom mus rau kev tswj hwm biofilm thiab enamel demineralization ib txhij.

Tshawb nrhiav qhov txuas ntawm Vitamin D thiab Dental Caries

Txoj kev tshawb no qhia txog Fer lub peev xwm ua kom ruaj khov SnF2, txhim khu kev ua haujlwm catalytic, thiab tsim cov yeeb yaj kiab tiv thaiv ntawm enamel, tiv thaiv demineralization yam tsis cuam tshuam rau lub qhov ncauj microbiome. Cormode hais tias, “Nws tsis yog hais txog inhibiting kab mob loj hlob los yog tiv thaiv cov enamel; Nws yog ib txoj kev holistic uas tsom rau ob qho tib si lom thiab physicochemical yam ntawm cov hniav caries. "

Tshaj li kev tiv thaiv kab mob caries, kev kho mob ua ke qhia tau hais tias kev cog lus hauv kev hais daws cov kab mob tsis muaj hlau tsis txaus, feem ntau ua ke nrog cov hniav lwj hauv cov menyuam yaus. Siv Fer tuaj yeem muab ob txoj kev daws teeb meem rau kev kho hniav thiab mob ntshav qab zib ib txhij.

Mus rau Clinical Applications

Ib qho txiaj ntsig ntxiv yog nyob rau hauv kev hloov pauv sai rau kev siv tshuaj kho mob. Fer qhov muaj nyob rau hauv qhov chaw tawm ntawm lub txee hlau oxide nanoparticle formulation qhia ib txoj hauv kev rau kev siv tswv yim thiab kev lag luam. Txawm li cas los xij, kev tshawb fawb ntxiv yog tsim nyog kom nkag siab txog cov txheej txheem hauv qab Fer thiab SnF2 synergy tag nrho.

Koo hais tias, "Txawm hais tias peb zoo siab nrog cov kev tshawb pom thawj zaug no, peb tseem tsom mus tob tob hauv kev nkag siab txog txoj kev sib txawv ntawm Fer thiab SnF2 kev sib koom ua ke los txhawb cov kev kho mob." Cormode underscores lub peev xwm ntawm qhov kev sib xyaw no tshaj li kev kho hniav, tawm tswv yim nws daim ntawv thov tawm tsam lwm yam biofilms.

Txoj kev tshawb no koom nrog cov kws tshawb fawb los ntawm ntau lub tsev kawm ntawv, suav nrog University of Pennsylvania, Northwestern University, thiab Indiana University, qhia txog kev sib koom tes rau kev kho hniav tshiab.

Txoj Kev Tshiab Muab Kev Cia Siab Hauv Kev Sib Tw Tawm Tsam Hniav Caries