NRT and Behavioral Therapy Yield Fivefold Increase in Smoking Cessation

INDIA: Nicotine Replacement Therapy (NRT) combined with behavioral therapy has demonstrated a groundbreaking impact, leading to nearly five times higher quit rates for smoking and tobacco use compared to counseling alone. 

The extensive study, conducted at the Tobacco Cessation Cell under the Department of Public Health Dentistry at SCB Dental College and Hospital in Cuttack, spanned from October 19, 2021, to January 31, 2023.

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Diverse Trial Groups and Extended Follow-Up

The trial involved 93 tobacco users, comprising both smokers and chewers, randomly assigned to three groups: nicotine gum, nicotine patch, or counselling only. Distinctively, the investigators provided extended follow-up for up to 26 weeks, surpassing the typical 12-week recommendation for NRT.

Dr. Utkal Mohanty, Associate Professor at the Department of Public Health Dentistry, SCB Dental College and Hospital, emphasized the significance of the results, stating, “Combined NRT and behavioral therapy resulted in nearly 5-fold higher quit rates compared to counseling alone. The clinical trial demonstrated the efficacy of NRT for both smokers and smokeless tobacco users.”

First-of-Its-Kind Study in Smokeless Tobacco Users

A notable aspect of the study is its documentation of NRT efficacy in chewers. Dr. Mohanty highlighted this achievement, noting, “This is the first-of-its-kind study in the world as no survey has documented efficacy of NRT in chewers.” Almost 70% of the trial participants were chewers, showcasing the potential of NRT in addressing smokeless tobacco use.

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The study underscores the transformative impact of a holistic approach to tobacco cessation. Relying solely on individual willpower has proven burdensome, and the trial advocates for a comprehensive strategy. 

Dr. Mohanty emphasized, “Integrating NRT with personalized behavioral support not only enhances quit rates but also provides vital guidance.”

Policy Implications and Accessibility

Referring to the study findings, health experts advocate for the over-the-counter availability of NRT, especially in remote areas. Dr. Chandrakant S Pandav, a global public health expert, emphasized the need for urgent accessibility. The study’s extended follow-up period showcased NRT’s potential as a readily available tool for lasting tobacco cessation.

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Dr. Chandrakant S Pandav expressed enthusiasm, calling the study a “game-changer against tobacco addiction.” Urging the continued availability of NRT over-the-counter, he highlighted its potential to liberate millions from tobacco’s grip, contributing to a healthier future.

WHO-Approved Therapy and Addressing Challenges

NRT is a WHO-approved therapy, recognized as the first line of treatment for tobacco cessation. It significantly reduces withdrawal symptoms and cravings, increasing the chances of quitting by 50-70% compared to unassisted attempts. The urgency to address tobacco challenges affecting a substantial percentage of the population is emphasized.

Dr. Sajeela Maini, Head of Tobacco Cessation and De-addiction at Sir Gangaram Hospital, stressed the importance of addressing both physiological and psychological aspects for effective treatment. She advocated for enhanced access to NRT, considering it a crucial supportive element in alleviating discomfort during the cessation process.

As India grapples with tobacco-related health concerns, the study’s findings are poised to influence policy discussions and pave the way for more accessible and comprehensive tobacco cessation programs.

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