USA: Dr. Geelsu Hwang at Penn Dental Medicine is engineering a revolutionary dental implant to tackle challenges associated with traditional implants. While dental implants have significantly improved dental care for millions of Americans, issues such as inflammation and gum disease can lead to implant failure over time. Dr. Hwang’s innovative approach aims to disrupt microbial biofilms, or plaque, which contribute to these complications.
Dr. Hwang explains the motivation behind the new implant design, highlighting the vulnerability of implants to disease compared to natural teeth. He states, “The lack of a good seal between the implant structure and the surrounding gum… means that the risk of disease around the implant is quite high.” To address this, the new implant will feature two key components aimed at combating peri-implant infection.
Nanoparticles and Phototherapy Integration
The crown of the implant will be infused with nanoparticles of barium titanate (BTO), a chemical compound known for its antibacterial properties. Additionally, the base of the crown will incorporate LEDs that emit light at a wavelength with antibacterial and anti-inflammatory properties. This phototherapy will be powered by the piezoelectric material in the crown, converting chewing or toothbrushing motion into electrical energy.
Dr. Hwang envisions broader applications for this innovative platform beyond dental implants, suggesting its potential integration into joint replacements and other medical devices. This demonstrates the versatility and potential impact of the technology beyond oral healthcare.
In 2023, Dr. Hwang received a five-year grant from the National Institutes of Health (NIH) to further develop the implant technology. The funding will support laboratory tests using human gum tissue cultures and subsequent trials in mini pigs, paving the way for future human clinical trials.
Additional Research Endeavors
Dr. Hwang’s research extends beyond dental implants, as he explores the development of a piezoelectric dental composite material for fillings. This material aims to inhibit bacterial colonization through enhanced electrical charge generation, offering a promising solution for dental restoration.
Dr. Geelsu Hwang’s pioneering work exemplifies the intersection of engineering and dental medicine, offering hope for improved outcomes in dental implant technology and oral healthcare as a whole.
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