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University Researchers Develop Cancer-Detecting Lollipops

UK: Researchers at the University of Birmingham have secured funding for a pioneering project aimed at developing mouth cancer-detecting lollipops. These innovative lollipops are poised to revolutionize the diagnosis of mouth cancer by enabling faster and less invasive detection.

The lollipops will be crafted using a sophisticated smart material known as hydrogel. This hydrogel is designed to capture proteins present in the patient’s saliva. Through the use of a fluorescent marker, the hydrogel effectively concentrates and labels these proteins, allowing for their observation under specific conditions.

Read: Study Reveals Oral Bacteria’s Role in Accelerating Pancreatic Cancer Development

Enhanced Diagnosis Process

The hydrogel-containing lollipop offers a less invasive alternative to current diagnostic methods, which often involve painful biopsies using flexible cameras. Early detection facilitated by these lollipops could significantly improve treatment outcomes for patients diagnosed with mouth cancer.


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With approximately 12,400 individuals diagnosed with head and neck cancers in the UK annually, the development of these cancer-detecting lollipops holds considerable promise for expediting diagnoses and reducing associated healthcare costs.

The project has received a £350,000 grant from Cancer Research UK and the Engineering and Physical Services Research Council, providing three years of funding. Dr. Ruchi Gupta, leading the research at the University of Birmingham, underscores the potential of smart hydrogels in diagnosing mouth cancer, highlighting their versatility in capturing proteins in saliva.

Read: Advancements in Oral Cancer Therapy: mRNA Lipid Nanoparticles

Future Prospects

While the current process of protein capture takes 12 hours, researchers aim to streamline this to just 10 minutes. Additionally, further testing is required to accurately differentiate the complex proteins associated with mouth cancer from other proteins present in saliva.

This research represents a significant advancement in the utilization of biocompatible hydrogels. Previously employed in tissue regeneration and drug delivery, hydrogels now offer a promising avenue for enhancing cancer diagnosis and treatment.

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