Human-on-a-Chip: 3D Printing Reproducing tib neeg cov ntaub so ntswg

BRAZIL: Cov kws tshawb fawb los ntawm São Paulo State Research Support Foundation (Visp) tau pib tsim kho cov cuab yeej hloov pauv uas hu ua "human-on-a-chip" lossis "lub cev-on-a-chip" (BoC), siv 3D tshuab luam ntawv. . 

Cov cuab yeej txiav no, muaj peev xwm tsim tau tib neeg cov ntaub so ntswg, tau ua qhov tseem ceeb hauv kev soj ntsuam cov tshuaj lom ntawm ntau yam khoom, kos lub cim tseem ceeb hauv kev tshawb fawb biomedical.

Kev siv hauv kev kuaj tshuaj lom neeg

BoC, uas rov tsim cov tawv nqaij thiab cov hnyuv, tau raug xa mus rau kev kuaj tshuaj lom hauv ntau lub tebchaws, suav nrog Brazil. Cov neeg ua lag luam loj, xws li tshuaj pleev ib ce loj Nature, tau txais kev siv tshuab no txij li thawj ib nrab xyoo 2023. 

Kev sib koom tes sib zog los hloov pauv 3D luam ntawv hauv Kev Kho Mob Khoom Siv

Biologist Juliana Lago piav qhia, "Peb siv cov khoom xyaw uas peb xav sim rau cov tawv nqaij rov tsim dua tshiab thiab ntsuas nws cov tshuaj lom, simulating kev ua ntawm tib neeg lub cev."

Txoj hauv kev tshiab no hais txog kev txhawj xeeb txog kev coj ncaj ncees yav dhau los cuam tshuam nrog kev ntsuas kev nyab xeeb thiab kev ua tau zoo, tshwj xeeb hauv kev zoo nkauj, kev nyiam huv ntawm tus kheej, thiab kev lag luam naj hoom. Los ntawm kev hloov cov kev sim tsiaj, uas tau txwv nyob rau lub Peb Hlis 2023 los ntawm National Council for the Control of Experiments on Animals (Concea), nrog BoC thev naus laus zis, cov kws tshawb fawb tuaj yeem ua cov tshuaj toxicity tag nrho thaum ua raws li cov qauv kev coj ncaj ncees.

Khoom siv thiab txheej txheem ntau lawm

Startup 3DBS, nyob hauv Campinas, Brazil, ua lub luag haujlwm tseem ceeb hauv kev tsim cov ntaub so ntswg tib neeg siv 3D tshuab luam ntawv. Cov ntaub so ntswg hauv plab yog tsim los ntawm cov hlwb uas tau txais los ntawm lub txhab nyiaj ntawm tes hauv Rio de Janeiro, thaum cov ntaub so ntswg ntawm daim tawv nqaij yog muab los ntawm tib neeg cov hlwb tau los ntawm cov ntaub so ntswg uas tau sau thaum phais. 

Biologist Ana Luisa Milas piav qhia, "Cells tshem tawm ntawm kev phais hauv cov menyuam yaus sai sai tsim hom I collagen, uas yog cov protein uas peb xav tau vim nws muab cov tawv nqaij tiv thaiv thiab elasticity."

Formlabs Unveils Resin Pumping System thiab Cov Khoom Siv rau Kev Txhim Kho 3D Printing

Tshaj li nws daim ntawv thov hauv kev tshawb fawb biomedical, 3D luam ntawv thev naus laus zis tau pom muaj ntau yam kev siv, suav nrog kev kho mob thiab kho hniav prosthetics, complex qhov chaw rau tsheb thiab aerospace industries, thiab zus tau tej cov kev cai los yog tsawg-ntim pwm thiab consumables. 

Tsis tas li ntawd, kev nce qib xws li kev loj hlob ntawm daim tawv nqaij nrog cov qauv zoo ib yam li cov hauv paus plaub hau los ntawm bio-printing tuav cov lus cog tseg rau yav tom ntej kho kev cuam tshuam hauv kev kho qhov txhab thiab kho graft.

Yav Tom Ntej Prospects thiab Kev Tshawb Fawb Tsis Txaus

Kev hloov pauv tsis tu ncua ntawm 3D luam ntawv thev naus laus zis qhib txoj hauv kev tshiab rau kev tshawb fawb tshawb fawb thiab kev kho mob tshiab. Nrog kev nce qib tas mus li thiab kev sib koom tes sib koom tes, cov kws tshawb fawb tsom mus siv lub peev xwm ntawm cov thev naus laus zis no los daws cov teeb meem kev noj qab haus huv nyuaj thiab txhim kho cov txiaj ntsig ntawm tus neeg mob.